On the Evaluation of the Hyperthermic Efficiency of Magnetic Scaffolds

Goal: Deep-seated tumors (DST) can be treated using thermoseeds exposed to a radiofrequency magnetic field for performing local interstitial hyperthermia treatment (HT). Several research efforts were oriented the manufacturing of novel biocompatible nanostructured thermo-seeds, called scaffolds (MagS). iron-doped bioceramics or polymers in various formulations are available. However, crucial evaluation their heating potential has been carried out with significantly different, lab specific, variable experimental conditions and protocols often ignoring several error sources inaccuracies estimation. xmlns:xlink="http://www.w3.org/1999/xlink">Methods: This work comments provides perspective analysis an protocol estimation methodology specific absorption rate (SAR) MagS DST HT. Numerical multiphysics simultions have performed outline theoretical framework. After silico analysis, case is considered tested. xmlns:xlink="http://www.w3.org/1999/xlink">Results: From simulations, we found that large overestimation SAR values found, due axial misplacement coil, while radial lower impact on estimated value. xmlns:xlink="http://www.w3.org/1999/xlink">Conclusions: The averaging multiple temperature records needed reliably effectively estimate